Dromostanolone mechanism of action

Gestrinone, also known as 17α-ethynyl-18-methyl-19-nor-δ 9,11 -testosterone, as well as 17α-ethynyl-18-methylestra-4,9,11-trien-17β-ol-3-one or as 13β-ethyl-18,19-dinor-17α-pregna-4,9,11-trien-20-yn-17β-ol-3-one, is a synthetic estrane steroid and a derivative of testosterone . [26] [14] It is more specifically a derivative of norethisterone (17α-ethynyl-19-nortestosterone) and is a member of the gonane (18-methylestrane) subgroup of the 19-nortestosterone family of progestins. [27] [10] [28] [29] Gestrinone is the C18 methyl derivative of norgestrienone (17α-ethynyl-19-nor-δ 9,11 -testosterone) and the δ 9,11 analogue of levonorgestrel (17α-ethynyl-18-methyl-19-nortestosterone) and is also known as ethylnorgestrienone due to the fact that it is the C13β ethyl variant of norgestrienone. [9] [30] It is also the C17α ethynyl and C18 methyl derivative of the AAS trenbolone . [31] [32]

Schering AG filed for a patent for NETA in June 1957, and the patent was issued in December 1960. [10] The drug was first marketed, by Parke-Davis as Norlestrin in the United States , in March 1964. [10] [11] This was a combination formulation of  mg NETA and 50 μg ethinylestradiol and was indicated as an oral contraceptive . [10] [11] Other early brand names of NETA used in oral contraceptives included Minovlar and Anovlar . [10]

Dromostanolone mechanism of action

dromostanolone mechanism of action

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