The actual cause of depression is not yet clear. However, doctors and scientists believe that it is a result of an imbalance in the chemicals signaling the brain. Studies are ongoing to identify the imbalance and the signaling chemicals. Various illnesses and some adverse life situations may spark depression. However, a majority of men with lower testosterone levels also exhibits depression signs. Most of them are obese or overweight. It points out the relation between depression and body fat. Average testosterone levels may reverse the situation for men.
GH can be used to treat conditions that produce short stature but are not related to deficiencies in GH. However, results are not as dramatic when compared to short stature that is solely attributable to deficiency of GH. Examples of other causes of shortness often treated with GH are Turner syndrome , chronic renal failure , Prader–Willi syndrome , intrauterine growth restriction , and severe idiopathic short stature . Higher ("pharmacologic") doses are required to produce significant acceleration of growth in these conditions, producing blood levels well above normal ("physiologic"). Despite the higher doses, side-effects during treatment are rare, and vary little according to the condition being treated.