Thank you Carol! I am so glad I found this post of yours as I am so confused and at a loss for what has happened to me after supplementing for MTHFR…For a bit of history, I recently started visiting a natural doctor after having about 2 years of not feeling like myself/chronic fatigue syndrome. I thought it was a result of unhealthy lifestyle in my early 20s now that I’m in my late 20s. Then I found all the online material on MTHFR mutation and read everything I could find. I was certain I had all the symptoms, but the symptoms are not very specific to this mutation vs other problems such as Thyroid/Adrenal etc. Sure enough, a month ago the blood work came back that I have 677TT (homozygous) and a normal 1298AA. For the last two years I have been religiously almost over supplementing when I didn’t know what was wrong with me, long before I recently found out about MTHFR. I was taking NAC, Glutathione, Milk Thistle blends from NOW/Gaia/Whole Foods, vitamin C, tumeric, SAMe, ALA, etc. The supplements helped a lot with energy, with the exception of SAMe, but the anxiety, insomnia, and fatigue would appear out of nowhere and freak me out because I had no explanation why. I should note, certain supplements like SAMe made my anxiety into mild depression so I stopped taking it. Anyways, now that I know about my gene mutation, I have isolated what I am taking to only active b9/b12. I have gotten my anxiety under control but am so fatigued in the morning, more than normal, and have brain fog all day for the last month I’ve been on methylfolate. I have tried both Dr. Lynch’s brand (800mcg methyl-folate, 1000mcg methyl-b12) and Jarrow (400mcg methyl-folate/1000mcg methyl-b12). I am certain it is making my brain not feel right for about 6 hours after taking it in the morning. Today I went and had a dumb 5-hour-energy shot because I knew it has 30mg of niacin and cheap folic acid. It made me feel so much better and alert. I honestly think I do not need methyl-folate even though I have this mutation, is that possible? Because I am not sure Dr. Lynch’s information is informative for everyone (perhaps just homozygous ones like myself), it can do more harm than good. I honestly think I was better off before just taking the liver assistance/methylation supplements and just knowing I need to avoid cheap folate in high doses and I should skip the methylfolate all together. That is what lead me here…looking for stuff like over/under methylation and histamine. If you have any advise, that would be much appreciated; as you noted, I feel very alone and even my wife thinks I’m crazy. The natural doctor is just recommending heavy methylfolate supplementation…I seriously feel like out of no where, after supplementing the methyl b vitamins, if I have wine or alcohol or any of my normal foods, I am having extreme histamine intolerance/high histamine feeling when I have never had any allergies before!
As for bodybuilders, Stanozolol has one interesting peculiarity demanded among them. It consists in the profound ability to lower sex hormone-binding globulin (SHBG) level resulting in efficiency growing of other steroids in stack with it. In particular, it raises the amount of biologically active free testosterone circulating in the blood. For this reason it is advisable always to use Stanozolol in stack with testosterone. Another one reason for this is as follows: Winstrol may be more prone than other anabolic steroids to increasing tendon brittleness. This happens due to Winstrol`s possibility to dry out the joint fluid, which can lead to joint pain and damages. Also both Stanozolol forms: tablets and injections have been noted to provoke adverse changes in cholesterol levels. Hence, monitoring of the lipid profile of the body (blood works) during cycle is advisable.
This office has produced a wide variety of designs, most much larger than the Precision 165. however, like all of our designs for Precision Boat Works, this latest effort is not less significant to us only less big. They have built all of our Precision designs with meticulous care, and we are proud of each and every one of them. We are confident that the new Precision 165 will quickly earn an equally enthusiastic following among yet another large and loyal group of new Precision owners.
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The studies I am familiar with show the positive effects of women-only spaces, I recognize that many believe those spaces can only be achieved by bureaucratically drawing and enforcing a line on the biologically assigned gender continuum. Instead I think they would find that men are generally not willing to even temporarily assume a female identity for spurious reasons. We call it identity for a reason. It is central to who we are. There are reasons women wish to infiltrate male-only clubs, and it is about power, not gender identity. Check the power dynamics and we may find that the line creating female-only spaces occurs organically and doesn’t need to be policed.
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