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Fossil evidence indicates that mastodons probably disappeared from North America about 10,500 years ago [1] as part of a mass extinction of most of the Pleistocene megafauna that is widely believed to have been a result of human hunting pressure. [42] [43] The latest Paleo-Indians entered the Americas and expanded to relatively large numbers 13,000 years ago, [44] and their hunting may have caused a gradual attrition of the mastodon population. [45] [46] Analysis of tusks of mastodons from the American Great Lakes region over a span of several thousand years prior to their extinction in the area shows a trend of declining age at maturation; this is contrary to what one would expect if they were experiencing stresses from an unfavorable environment, but is consistent with a reduction in intraspecific competition that would result from a population being reduced by human hunting. [46]

The Oxandrolone hormone does not carry any estrogenic related side effects. It does not aromatize and cannot lead to gynecomastia or water retention due to increases in estrogen levels. It further carries no progestin related activity, which again supports no estrogenic related side effects. Due to water retention being impossible with this steroid, this will decrease the risk of high blood pressure. Excess water retention can promote high blood pressure. Some steroids that do not aromatize can lead to high blood pressure, such as Trenbolone , but Anavar is rarely associated with this trait.
 

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According to the US Food and Drug Administration , "Piracetam is not a vitamin, mineral, amino acid, herb or other botanical, or dietary substance for use by man to supplement the diet by increasing the total dietary intake. Further, piracetam is not a concentrate, metabolite, constituent, extract or combination of any such dietary ingredient. [...] Accordingly, these products are drugs, under section 201(g)(1)(C) of the Act, 21 . § 321(g)(1)(C), because they are not foods and they are intended to affect the structure or any function of the body. Moreover, these products are new drugs as defined by section 201(p) of the Act, 21 . § 321(p), because they are not generally recognized as safe and effective for use under the conditions prescribed, recommended, or suggested in their labeling." [110]

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