Dianabol is a relatively strong estrogenic anabolic steroid due to the moderate level of aromatase activity it carries. While its aromatase activity is only moderate, this conversion actually leads Methandrostenolone to be converted to methylestradiol rather than estradiol, which is far more powerful than estradiol. This can make side effects like gynecomastia and water retention very possible with this steroid; in fact, they can appear seemingly overnight. Heavy water retention can also promote high blood pressure, which Dianabol is notorious for causing. Such effects can be controlled, and when it comes to high blood pressure this is something you’ll need to put some effort into ensuring does not become a problem.
In order to combat the estrogenic side effects of Dianabol, anti- estrogens are commonly recommended when supplementing with this steroid. You have two choices in anti-estrogens, Selective Estrogen Receptor Modulators (SERM’s) like Nolvadex ( Tamoxifen Citrate ) and Aromatase Inhibitors (AI’s) like Femara ( Letrozole ). SERM’s can be enough for some men and should be your first choice if they can get the job done. However, AI’s will be far more effective as they will directly inhibit aromatization and reduce serum estrogen levels. Unfortunately, AI’s can negatively affect cholesterol, as can Dianabol, and when conjoined this can prove potentially problematic. If an AI is used cholesterol management will be a priority, and it will be possible. However, SERM’s, while not always as effective will actually promote healthier cholesterol levels due to their estrogenic like activity in the liver.
Methandienone (also known as methandrostenolone, Dbol, dianabol) is an orally-effective anabolic steroid originally developed in Germany and released in the US in the early 1960s by Ciba Specialty Chemicals. This is a derivative from testosterone, one of the most popular steroid compounds in the world and the second steroid (after testosterone) ever produced. Methandienone promotes dramatic increases in protein synthesis, glycogenolysis, and muscle strength over a short space of time.
As an example, should you choose to run a cycle that includes both Dianabol and Anavar, you will need to be extremely careful when it comes to overlapping them. The two are both hepatotoxic, which means they will cause liver damage. You will need to consider this carefully when it comes to choosing cycle lengths. If you take Dianabol for four weeks at the beginning of your cycle, then make the switch to Anavar, you should limit your Anavar use to four weeks, as well. This reduces your entire cycle time to eight weeks, which helps to alleviate some of the risk of liver damage.